Particle Coating, Taste Masking & Pelletization
ثبت نشده
چکیده
منابع مشابه
A Novel Strategy for Bitter Taste Masking of Gankeshuangqing Dispersible Tablets Based on Particle Coating Technology
BACKGROUND Currently, acute upper respiratory tract infections (AURTIs) are increasingly becoming a significant health burden. Gankeshuangqing dispersible tablets (GKSQDT) which have a good effect on treating AURTIs. GKSQDT is composed of baicalin and andrographolide. However, its severe bitterness limits application of patients. Due to the addition of plentiful accessories, common masking meth...
متن کاملTaste masking of roxithromycin by spray drying technique.
The spray drying technique was used to obtain the roxithromycin containing microcapsules with high taste masking efficiency. Eudragit L30D-55 was chosen as a barrier coating. The taste was evaluated by an electronic tongue, and taste-masking effect in water lasted at least several dozen hours.
متن کاملTaste Masking Technology: Recent Developments and Approaches
Taste-masking technologies are important for obtaining high-patient compliance and drug therapy efficiency, since many oral-delivery drugs have unpleasant qualities such as bitterness, sourness or saltiness. Taste-masking technology includes two aspects: selection of appropriate tastemasking substances (polymers, flavourings, sweeteners, amino acids, etc.) and selection of appropriate taste-mas...
متن کامل[Preparation of orally disintegrating tablets for masking of unpleasant taste: comparison with corrective-adding methods].
Many orally disintegrating tablets have recently been developed to improve oral ingestion and usability and are widely administered clinically, resulting in improved quality of life for patients. Since orally disintegrating tablets rapidly disintegrate in the mouth, the masking of unpleasant taste is important. We investigated the masking of the taste of furosemide (FU) as a model drug with cor...
متن کاملDevelopment and optimization of taste-masked orally disintegrating tablets (ODTs) of clindamycin hydrochloride.
The purpose of this research was to develop an orally disintegrating tablet (ODT) dosage form containing taste-masked beads of clindamycin HCl. Several formulation strategies were evaluated and a taste-masked ODT of clindamycin HCl was prepared without the use of a waxy cushioning agent. Clindamycin HCl (ca. 46% w/w) was coated onto microcrystalline cellulose beads (Cellets® 200) followed by th...
متن کامل